개요

  • HOME
  • 출판물
  • 한국섬유공학회지
  • 개요
  • Prev.
    한국섬유공학회지, Vol.54, No.6, pp. 456-461, 2017
    동축 전기방사를 통해 제조된 PLA Sheath-core 나노섬유의 제조 및 특성분석
    Fabrication and Characterization of PLA Sheath-core Nanofibers by Coaxial Electrospinning
     
    김민희 · 김희철 · 박원호
     
    In this study, poly(lactic acid) (PLA) nanofibers with sheath-core structure was prepared by coaxial electrospinning. The morphology of PLA sheath-core nanofibers was characterized using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). The PLA nanofibers with sheath-core structure was successfully fabricated by coaxial electrospinning, and the loading of model drug was controlled by solution feed ratio. In addition, the dual drug release of PLA nanofibers was evaluated in the physiological media. From the results, the cumulative release rate of model drug in sheath part was higher than that in core part. The PLA sheath-core nanofibers has a great potential for drug delivery system and scaffolds for tissue engineering.
     
    Keywords : poly(lactic acid), coaxial electrospinning, nanofibers, sheath-core, dual drug release
    DOI : https://doi.org/10.12772/TSE.2017.54.456
     
    Full text(PDF)  동축 전기방사를 통해 제조된 PLA Sheath-core 나노섬유의 제조 및 특성분석